Vitamine A kan in overmaat toxische reacties uitlokken, zowel acuut als chronisch. Zelfs gewone voeding schijnt te veel vitamine A te kunnen bevatten, maar dan blijft nog de vraag vanaf welke dagelijkse hoeveelheid die nadelige effecten optreden. Recent werd een nieuwe functie aan vitamine A toegekend, nog wel als cofactor in de mitochondriën.
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