1. Osborne, T.B., Mendel, L.B., Ferry, E.L., 1917. The effect of retardation of growth upon the breeding period and duration of life in rats. Science 45, 294-295.

2. McCay, C.M., Crowell, M.F., Maynard, L.A., 1935. The effect of retarded growth upon the length of life and upon the ultimate body size. J Nutr. 10, 63-79

3. Masoro EJ. Dietary restriction-induced life extension: a broadly based biological phenomenon. Biogerontology (2006) 7: 153-155

4. Shanley DP, Kirkwood T. Caloric restriction does not enhance longevity in all species and is unlikely to do so in humans. Biogerontology (2006) 7: 165-168

5. Phelan JP, Rose MR. Caloric restriction increases longevity substantially only when the reaction norm is steep. Biogerontology (2006) 7: 161-164

6. Dehmelt H. Re-adaptation hypothesis: explaining health benefits of caloric restriction. Med Hypothes. 2004; 62:620-624

7. Sohal RS, Allen RG. Relationship between metabolic rate, free radicals, differentiation and aging: a unified theory. Basic Life Sci 1985; 35:75-104

8. Civitaresse AE, Carling S et al. Calorie Restriction Increases Muscle Mitochondrial Biogenesis in Healthy Humans. PLoS Medicine. 2007;4(3):e76-e85

9. Fontana L, Weiss EP et al. Long-term effects of calorie or protein restriction on serum IGF-1 and IGFBP-3 concentration in humans. Aging Cell (2008) 7:681-687

10. Morley JE, Chahla E et al. Antiaging, longevity and calorie restriction. Current Opinion in Clinical Nutrition and Metabolic Care 2010; 13:40-45

11. Colman RJ, Anderson RM, Johnson SC et al. Caloric restriction delays disease onset and mortality in rhesus monkeys. Science. 2009 Jul 10;325(5937):201-4.

12. Redman LM, Martin CK et al. Effect of Caloric Restriction in Non-Obese Humans on Physiological, Psychological and Behavioral Outcomes. Physiol Behav. 2008 August 6; 94(5): 643–648

13. Johnson JB, Laub DR et al. The effect on health of alternate day calorie restriction: Eating less and more than needed on alternate days prolongs life. Medical Hypotheses (2006) e-publicatie

14. Redman LM, Martin CK et al. Effect of Caloric Restriction in Non-Obese Humans on Physiological, Psychological and Behavioral Outcomes. Physiol Behav. 2008 August 6; 94(5): 643–648

15. Fontana L, Villareal DT et al. Calorie restriction or excercise: effects on coronary heart disease risk factors. A randomized, controlled trial. Am J Physiol Endocrinol Metab. 2007; 293:E197-E202

16. Lee IS, Shin G, Choue R. A 12-week regimen of caloric restriction improves levels of adipokines and pro-inflammatory cytokines in Korean women with BMIs greater than 23 kg/m2. Inflamm Res. 2010May;59(5):399-405. Epub 2009 Nov 16.

17. Seyfried BT, Kiebish M, Marsh J, Mukherjee P. Targeting energy metabolism in brain cancer through calorie restriction and the ketogenic diet. J Cancer Res Ther. 2009 Sep;5 Suppl 1:S7-15

18. Ong KR, Sims AH et al. Biomarkers of dietary energy restriction in women at increased risk of breast cancer. Cancer Prev Res (Phila Pa). 2009 Aug;2(8):720-31.

19. Papadopoulos FC, Pantziaras I, Lagiou P, Brandt L, Ekselius L, Ekbom A. Age at onset of anorexia nervosa and breast cancer risk. Eur J Cancer Prev. 2009 Jun;18(3):207-11.

20. Lillian de Jonge, Emilia AM Moreira et al. Impact of six-month caloric restriction on autonomic nervous system activity in healthy, overweight, individuals. Obesity (Silver Spring). 2010 February; 18(2):414–416.

21. Kristan DM. Calorie restriction and susceptibility to intact pathogens. Age (Dordr). 2008 September;30(2-3): 147–156.

22. Morley JE, Chahla E et al. Antiaging, longevity and calorie restriction. Current Opinion in Clinical Nutrition and Metabolic Care 2010, 13:40-45

23. Heilbronn LK, Ravussin E. Calorie restriction and aging: review of the literature and implications for studies in humans. Am J Clin Nutr 2003;78:361–9

24. Masoro EJ. Role of hormesis in life extension by caloric restriction. Dose-Response, 5:163-173. 2007

25. Nandy K. Effects of controlled dietary restriction on brain-reactive antibodies in sera of aging mice. MechAgeing Dev. 1982; 18

26. Silvermann NE et al. Addition of aerobic exercise to a weight loss program increases BMD with an associated reduction in inflammation in overweight postmenopausal women. Calcif Tissue Int. 2009; 84

27. Johnson JB et al. The effect on health of alternate day calorie restriction: eating less and more than needed on alternate days prolongs life. Med Hypotheses. 2006; 67:209-211

28. Caro P et al. Effect of 40% restriction of dietary amino acids except methionine on mitochondrial oxidative stress and biogenesis, AIF and SIRT1 in rat liver. Biogerontology. 2009; 10:579-592